Titre : Intelligent Micro-and Nanocontainers for Applications in Materials- and Biosciences.
Cette conférence sera prononcée par le professeur Helmuth Möhwald du département des interfaces du Max Planck Institute of Colloids and Interfaces. Elle est commanditée par le Centre de recherche sur les materiaux auto-assemblés (CRMAA) et sera donnée en anglais.
Résumé : Having learnt to control structure and properties of ultrathin films this enables one to study their application in many areas. This can be on one hand via construction of multilayer capsules, on the other hand, and this is a focus of this presentation, by preparing a permselective coating on loaded porous containers. Examples of cores are calcium carbonate,-phosphate or silica nanoparticles, halloysites as peculiar clay nanotubes and polymeric core/ shell particles. These inorganic templates can also be used to prepare defined organic particles like loosely packed insulin microparticles. It will be shown that one thus can prepare intelligent feedback active systems that in a coating exhibit tunable compatibility with the matrix. Concrete applications are light or pressure induced intracellular drug release to trigger and follow cellular processes, use of interacting capsules to establish coupled enzymatic reactions, embedment in anticorrosion and antibacterial coatings with enhanced mechanics, adhesion and self-repair. The presentation will also concentrate on mechanistic aspects of the applications like cellular response and corrosion.
